हिंदी साहित्य: पेन ड्राइव कोर्स
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Important Facts For Prelims

Aspirin to Prevent Cataract

  • 03 Aug 2020
  • 2 min read

Why in News

Recently, scientists from the Institute of Nano Science & Technology (INST) have developed nanorods from the Non-Steroidal Anti-Inflammatory Drug (NSAID) Aspirin to prevent cataracts in an economical and less complicated way.

  • Aspirin is a popular medication used to reduce pain, fever, or inflammation and now it has been found to be an effective non-invasive small molecule-based nanotherapeutics against cataract.
  • INST is an autonomous institute under the Department of Science and Technology, Government of India.

Key Points

  • Cataract:
    • It is a major form of blindness that occurs when the structure of crystallin proteins that make up the lens in human eyes deteriorates.
    • Such deterioration causes damaged or disorganised proteins to aggregate and forms a milky blue or brown layer, which ultimately affects lens transparency.
    • As with ageing and under various conditions, the lens protein crystallin aggregates to form opaque structures in the eye lens, which impairs vision and causes cataract.
    • Thus, prevention of the formation of these aggregates as well as their destruction in the early stage of disease progression is a major treatment strategy for cataracts.
  • Usage of Aspirin:
    • The scientists have used the anti-aggregation ability of self-build aspirin nanorods as an effective non-invasive small molecule-based nanotherapeutics against cataract.
    • It prevents the protein from aggregation through biomolecular interactions, which convert it into coils and helices and consequently fail to aggregate.
  • Significance:
    • Aspirin nanorods due to their nano-size are expected to enhance the bioavailability, improve drug loading, lower toxicity, etc.
    • Hence, the delivery of the aspirin nanorods as eye drops is going to serve as an effective and viable option to treat cataract non-invasively.
    • It is easy to use and a low-cost alternative nonsurgical treatment method and will benefit patients in developing countries who cannot access expensive cataract treatments and surgeries.

Source: PIB

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