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Multisystem Inflammatory Syndrome in Children

  • 17 Apr 2021
  • 2 min read

Why in News

Recently, doctors in the United States have reported neurological symptoms in children with Multisystem Inflammatory Syndrome in Children (MIS-C).

Key Points

  • Multisystem Inflammatory Syndrome in Children (MIS-C):
    • MIS-C is a rare but severe hyperinflammatory condition in children and adolescents that typically occurs 2-6 weeks after a Covid-19 infection.
    • It is a potentially deadly condition where different body parts can become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs.
    • Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, bloodshot eyes, or feeling extra tired.
  • MIS-C with Neurological Complications:
    • In a recent study, young people with the MIS-C syndrome have shown neurological issues which were life-threatening such as strokes or severe encephalopathy (any brain disease that alters brain function or structure).
    • Neurological symptoms include hallucinations, confusion, speech impairments, and problems with balance and coordination.
    • The new findings strengthen the theory that the syndrome is related to a surge of inflammation triggered by an immune response to the virus.
  • Causes of MIS-C:
    • As the Syndrome is less researched, there are varied theories as to what causes MIS-C.
    • While some researchers believe that MIS-C is a delayed response to the coronavirus which in turn causes massive inflammation in the body and as a result damages organs.
    • Some believe that it can also be a result of the children’s immune response making antibodies against the virus.
    • There may be a genetic component as not every child develops MIS-C and the presenting symptoms are so varied.
  • Treatment:
    • It involves symptonic relief such as supportive care or use of various medicines to treat inflammation.

Source: IE

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