Escherichia coli bacteria | 19 Aug 2025

Source:TH    

Researchers have successfully transformed genetically engineered Escherichia coli bacteria (E. coli) into self-powered chemical sensors. 

• E. coli, a Gram-negative, rod-shaped bacterium in the Enterobacteriaceae family, resides in human and animal intestines. It helps maintain gut microbiota balance and indicates fecal water contamination. 

Engineered E. coli 

• About: Engineered E. coli acts as a bio-sensor, capable of detecting chemicals, processing signals, and producing electrical outputs. 
• Significance:  Traditional biosensors, like enzyme-based ones, are fragile, costly, and slow in complex environments. Whole-cell biosensors using living microorganisms can self-repair and function in contaminated samples. 
  • It can be used as a cheaper, robust, and programmable alternative to conventional enzyme-based biosensors. 
• Applications: Biosensors detect water toxins, monitor pollution, warn public health risks, work with portable electronics, and advance programmable bioelectronics.