Agappe Chitra Magna Kit for Covid-19 | 21 May 2020

Why in News

The Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) in collaboration with Agappe Diagnostics Ltd. has commercially launched the Agappe Chitra Magna Kit for detection of Covid-19.

  • SCTIMST is an Institute of National Importance under the Department of Science and Technology (DST).

Key Points

  • Agappe Chitra Magna is a magnetic nanoparticle-based RiboNucleic Acid (RNA) extraction kit.
  • Working:
    • It isolates RNA from the patient sample using magnetic nanoparticles.
      • SARS-COV-2, the causative virus of Covid-19 pandemic, is an RNA virus- a long single-stranded polymeric substance present in all living cells that carries the genetic information of the organism necessary for life.
      • One of the critical steps in detecting this virus is by confirming the presence of the RNA of the virus in the sample taken from the throat or nose.
    • The magnetic nanoparticle beads bind to the viral RNA and, when exposed to a magnetic field, give a highly purified and concentrated RNA.
    • As the sensitivity of the detection method is dependent on getting an adequate quantity of viral RNA, this innovation enhances the chances of identifying positive cases.
  • Application:
    • The kit can be used for RNA extraction for RT-LAMP, RT-PCR and other isothermal and Polymerase Chain Reaction (PCR) based protocols for the detection of SARS-COV-2.
  • Significance:
    • The indigenously developed and manufactured RNA extraction kit would reduce the nation’s dependence on imported kits which are expensive and thus will bring down the cost of Covid-19 testing.

Source: PIB